Canagliflozin

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Product Code: 3087
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$461.00

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Canagliflozin is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.

Chemical Name (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol

Biological Activity:
Biological Activity	Canagliflozin is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.
Technical Data:
M.W.	444.52
Formula:	<p>C<sub>24</sub>H<sub>25</sub>FO<sub>5</sub>S</p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	842133-18-0
References:
References	Liang Y, et al. PLoS One. 2012, 7(2), e30555. Nomura S, et al. J Med Chem. 2010, 53(17), 6355-6360.

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