Dapagliflozin

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Product Code: 3109
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$398.00

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Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 3.

Chemical Name:

(2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol

Biological Activity:
Biological Activity	Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 3.
Technical Data:
M.W.	408.87
Formula:	C<sub>21</sub>H<sub>25</sub>ClO<sub>6</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	461432-26-8
References:
References	Meng W, et al. J Med Chem, 2008, 51(5), 1145-1149. Han S, et al. Diabetes, 2008, 57(6), 1723-1729. Obermeier M, et al. Drug Metab Dispos, 2010, 38(3), 405-414. Macdonald FR, et al. Diabetes Obes Metab, 2010, 12(11), 1004-1012.

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