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SKI II

SKI II

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Product Code: 3250
Availability: In Stock
$180.00
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SKI II is a highly selective and non ATP-competitive S1P receptor inhibitor with IC50 of 0.5 μM, while exhibits no inhibitory on other kinases including PI3K, PKCα and ERK2.

Chemical Name:
Phenol, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-
 

Inhibitors GPCR & G Protein S1P Receptor SKI II 312636-16-1
Biological Activity:
Biological Activity SKI II is a highly selective and non ATP-competitive S1P receptor inhibitor with IC50 of 0.5 μM, while exhibits no inhibitory on other kinases including PI3K, PKCα and ERK2.
Technical Data:
M.W. 302.78
Formula: C<sub>15</sub>H<sub>11</sub>ClN<sub>2</sub>OS
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 312636-16-1
References:
References French KJ, et al. Cancer Res, 2003, 63(18), 5962-5969. French KJ, et al. J Pharmacol Exp Ther, 2006, 318(2), 596-603. Zhu ZA, et al. Asian Pac J Cancer Prev, 2012, 13(2), 625-631. Chiba Y, et al. J Pharmacol Sci, 2010, 114(3), 304-310.

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