Clemastine Fumarate

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Product Code: 3093
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Clemastine Fumarate (Clemastine) is a selectivehistamine H1 receptor antagonist with IC50 of 3 nM.

Chemical Name Pyrrolidine, 2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, (2R)-, (2E)-2-butenedioate

Biological Activity:
Biological Activity	Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.
Technical Data:
M.W.	459.96
Formula:	<p>C<sub>21</sub>H<sub>26</sub>ClNO.C<sub>4</sub>H<sub>4</sub>O<sub>4</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	14976-57-9
References:
References	Seifert R, et al. Mol Pharmacol, 1992, 42(2), 227-234. Nair MP, et al. Cell Immunol, 1983, 81(1), 45-60. Merlos M, et al. J Pharmacol Exp Ther, 1997, 280(1), 114-121. Ridley JM, et al. J Mol Cell Cardiol, 2006, 40(1), 107-118. N?renberg W, et al. J Biol Chem, 2011, 286(13), 11067-11081. Blazs G, et al. Pharmacol Res, 1997, 35(1), 65-71.

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