TPCA-1

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Product Code: 3204
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TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1.

Chemical Name:
2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid

Biological Activity:
Biological Activity	TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1.
Technical Data:
M.W.	279.29
Formula:	C<sub>12</sub>H<sub>10</sub>FN<sub>3</sub>O<sub>2</sub>S
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	507475-17-4
References:
References	Podolin PL, et al, J Pharmacol Exp Ther, 2005, 312(1), 373-381. Du Z, et al, J Interferon Cytokine Res, 2012, 32(8), 368-377.

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TPCA-1

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