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Azithromycin

Azithromycin

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Product Code: 3051
Availability: In Stock
$117.00
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Azithromycin is an antibiotic for inhibition of parasite growth with IC50 of 8.4 μM.

Chemical Name: 13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one

Inhibitors Ubiquitin Autophagy Azithromycin 83905-01-5
Biological Activity:
Biological Activity Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models.
Technical Data:
M.W. 748.98
Formula: C<sub>38</sub>H<sub>72</sub>N<sub>2</sub>O<sub>12</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 83905-01-5
References:
References Girard et al (1987) Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with extended half-life and excellent tissue distribution. Antimicrob.Agents Chemother. 31 1948. PMID: 2830841. Retsema et al (1987) Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. Antimicrob.Agents Chemother. 31 1939. PMID: 2449865.

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