PYR-41

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Product Code: 3298
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PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.

Chemical Name Benzoic acid, 4-[4-[(5-nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]-, ethyl ester

Biological Activity:
Biological Activity	PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
Technical Data:
M.W.	371.3
Solubility:	<p>C<sub>17</sub>H<sub>13</sub>N<sub>3</sub>O<sub>7</sub></p>
Purity:	DMSO
Storage:	98%
CAS No:	418805-02-4
References:
References	Yang Y, et al. Cancer Res, 2007, 67(19), 9472-9481. Kapuria V, et al. Biochem Pharmacol, 2011, 82(4), 341-349.

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PYR-41

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