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Degrasyn

Degrasyn

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Product Code: 3114
Availability: In Stock
$398.00
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WP1130 (Degrasyn) is a selective deubiquitinase(DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also suppresses Bcr/Abl, also a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).

Chemical Name

(S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide

Inhibitors Ubiquitin DUB Degrasyn 856243-80-6
Biological Activity:
Biological Activity WP1130 (Degrasyn) is a selective deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also suppresses Bcr/Abl, also a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).
Technical Data:
M.W. 384.27
Formula: C<sub>19</sub>H<sub>18</sub>BrN<sub>3</sub>O
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 856243-80-6
References:
References Bartholomeusz GA, et al. Blood, 2007, 109(8), 3470-3478. Bartholomeusz G, et al. Cancer Res, 2007, 67(8), 3912-3918. Kapuria V, et al. Cancer Res, 2010, 70(22), 9265-9276.

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