Wishlist (0)
Welcome visitor Login or Register.
My Cart    0 $0.00
Your shopping cart is empty!
Carfilzomib

Carfilzomib

0 reviews Write a review
Product Code: 3088
Availability: In Stock
$335.00
-+

Carfilzomib (PR-171) is an irreversible proteasomeinhibitor with IC50 of <5 nM, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities.

Chemical Name L-Phenylalaninamide, (αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-

Inhibitors Ubiquitin Proteasome Carfilzomib (PR-171) 868540-17-4
Biological Activity:
Biological Activity Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities.
Technical Data:
M.W. 719.91
Formula: <p>C<sub>40</sub>H<sub>57</sub>N<sub>5</sub>O<sub>7</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 868540-17-4
References:
References Kuhn DJ, et al. Blood. 2007, 110(9), 3281-3290. Kuhn DJ, et al. Curr Cancer Drug Targets. 2011, 11(3), 285-295. Hurchla MA, et al. Leukemia. 2012. Dasmahapatra G, et al. Mol Cancer Ther. 2011, 10(9), 1686-1697.

Write a review

Note: HTML is not translated!
    Bad           Good
Continue

About HDH PHARMA

At HDH Pharma, we are committed to offering our clients the highest quality research services with the most convenient and effective communications from both US and Indian operations. Clients in the Americas and Europe can pick up the phone and speak directly with our scientists in the US. Clients in Asia can receive the same rapid response from our scientists in India. HDH’s hybrid operation is designed with our client’s operational needs in mind.


Information

Extras

My Account

Powered By Nsoft Solutions
HDH PHARMA © 2024