MG-132

MG-132

Product Code: 3381
Availability: In Stock
$209.00
-+

MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.

Chemical Name benzyl (S)-4-methyl-1-((S)-4-methyl-1-((S)-4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate

Biological Activity:
Biological Activity MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.
Technical Data:
M.W. 475.62
Formula: <p>C<sub>26</sub>H<sub>41</sub>N<sub>3</sub>O<sub>5</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 133407-82-6
References:
References Tsubuki S, et al. J Biochem, 1996, 119(3), 572-576. Fiedler MA, et al. Am J Respir Cell Mol Biol, 1998, 19(2), 259-268. MacLaren AP, et al. Cell Death Differ, 2001, 8(3), 210-218. Crawford LJ, et al. Cancer Res, 2006, 66(12), 6379-6386. Li W, et al. Cancer Res, 2007, 67(5), 2247-2255. Diallo JS, et al. Br J Cancer, 2008, 99(10), 1613-1622. Bonuccelli G, et al. Am J Pathol, 2003, 163(4), 1663-1675. Caron AZ, et al. BMC Musculoskelet Disord, 2011, 12:185.

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