RG108

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Product Code: 3283
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RG108 is an inhibitor of DNA methyltransferase withIC50 of 115 nM, does not cause trapping of covalent enzymes.

Chemical Name 1H-Indole-3-propanoic acid, α-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, (αS)-

Biological Activity:
Biological Activity	RG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM, does not cause trapping of covalent enzymes.
Technical Data:
M.W.	334.33
Formula:	<p>C<sub>19</sub>H<sub>14</sub>N<sub>2</sub>O<sub>4</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	48208-26-0
References:
References	Brueckner B, et al, Cancer Res, 2005, 65(14), 6305-6311. Schirrmacher E, et al, Bioconjug Chem, 2006, 17(2), 261-266. Pasha Z, et al, PLoS One, 2011, 6(8), e23667.

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