Decitabine

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Product Code: 3113
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Decitabine is a potent inhibitor of DNA methylation withIC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.

Chemical Name:

4-amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one

Biological Activity:
Biological Activity	Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively
Technical Data:
M.W.	228.21
Formula:	C<sub>8</sub>H<sub>12</sub>N<sub>4</sub>O<sub>4</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	2353-33-5
References:
References	Shaker S, et al. Leuk Res, 2003, 27(5), 437-444. Hassler MR, et al. Biochimie, 2012, doi.org/10.1016/j.biochi.2012.05.029.

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