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Veliparib

Veliparib

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Product Code: 3193
Availability: In Stock
$146.00
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Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. It is inactive to SIRT2. Phase 1/2.

Chemical Name:
(R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide

Inhibitors Epigenetics PARP Veliparib 912444-00-9
Biological Activity:
Biological Activity Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. It is inactive to SIRT2. Phase 1/2.
Technical Data:
M.W. 244.29
Formula: C<sub>13</sub>H<sub>16</sub>N<sub>4</sub>O
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 912444-00-9
References:
References Donawho CK, et al, Clin Cancer Res, 2007, 13 (9), 2728-2737. Penning TD, et al, J Med Chem, 2009, 52(2), 514-523. Albert JM, et al, Clin Cancer Res, 2007, 13(10), 3033-3042. Kinders RJ, et al, Clin Cancer Res, 2008, 14(21), 6877-6885.

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