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Etoposide

Etoposide

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Product Code: 3138
Availability: In Stock
$83.00
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Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity.

Chemical Name Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-

Inhibitors DNA Damage Topoisomerase Etoposide 33419-42-0
Biological Activity:
Biological Activity Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity.
Technical Data:
M.W. 588.56
Formula: C<sub>29</sub>H<sub>32</sub>O<sub>13</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 33419-42-0
References:
References van Maanen JM et al, J Natl Cancer Inst, 1988, 80(19), 1526-1533. Ma G, et al. J Dermatol Sci, 2000, 24(2), 126-133. Kalwinsky DK, et al. Cancer Res, 1983, 43(4), 1592-1597. Slater LM, et al. Cancer Chemother Pharmacol, 2001, 48(4), 327-332. Beauchesne P, et al. Cancer Chemother Pharmacol, 1998, 41(2), 93-97. Fuchs J, et al. Cancer, 1998, 83(11), 2400-2407. Kaneko M, et al. Gan To Kagaku Ryoho, 1991, 18(7), 1155-1161. Nagai S, et al. J Surg Oncol, 1993, 54(4), 211-215. Slater LM, et al. Cancer Chemother Pharmacol, 2001, 48(4), 327-332.

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