Vincristine

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Product Code: 3189
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Vincristine is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM.

Chemical Name:
1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone

Biological Activity:
Biological Activity	Vincristine is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM.
Technical Data:
M.W.	923.04
Formula:	C<sub>46</sub>H<sub>58</sub>N<sub>4</sub>O<sub>14</sub>S
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	2068-78-2
References:
References	Jordan MA, et al. Cancer Res, 1985, 45(6), 2741-2747. Gidding CE. Crit Rev Oncol Hematol, 1999, 29(3), 267-287. Tu Y, et al. Int J Mol Med, 2013, 31(1), 113-119. Donoso JA, et al. Cancer Res, 1977, 37(5), 1401-1407. Horton JK, et al. Biochem Pharmacol, 1988, 37(20), 3995-4000. Baguley BC, et al. Eur J Cancer, 1991, 27(4), 482-487.

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