AZ 3146

AZ 3146

Product Code: 3042
Availability: In Stock
$184.00
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AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.

Chemical Name: 9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one

Biological Activity:
Biological Activity AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
Technical Data:
M.W. 452.55
Formula: C<sub>24</sub>H<sub>32</sub>N<sub>6</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 1124329-14-1
References:
References Hewitt L, et al. J Cell Biol, 2010, 190(1), 25-34.

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