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TAE226

TAE226

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Product Code: 3236
Availability: In Stock
$335.00
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NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.

Chemical Name:

Benzamide, 2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-

Inhibitors Cytoskeletal Signaling FAK TAE226 761437-28-9
Biological Activity:
Biological Activity NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.
Technical Data:
M.W. 468.94
Formula: C<sub>23</sub>H<sub>25</sub>ClN<sub>6</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 761437-28-9
References:
References Liu TJ, et al. Mol Cancer Ther, 2007, 6(4), 1357-1367. Beierle EA, et al. Cancer Invest, 2008, 26(2), 145-151. Schultze A, et al. Invest New Drugs, 2010, 28(6), 825-833. Hatakeyama S, et al. 2006, ASCO Annual Meeting. Abst 13162. Kawahara E, et al. 2006, ASCO Annual Meeting. Abst 13163.

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