Nutlin-3a

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Product Code: 3339
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$839.00

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Nutlin-3a, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM.

Chemical Name 2-Piperazinone, 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-

Biological Activity:
Biological Activity	Nutlin-3a, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM.
Technical Data:
M.W.	581.49
Formula:	<p>C<sub>30</sub>H<sub>30</sub>Cl<sub>2</sub>N<sub>4</sub>O<sub>4</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	675576-98-4
References:
References	Tovar C, et al. Proc Natl Acad Sci U S A, 2006, 103(6), 1888-1893. Ohnstad HO, et al. BMC Cancer, 2011, 11(211), 1-11. Vassilev LT, et al. Science, 2004, 303(5659), 844-848.

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