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Nutlin-3

Nutlin-3

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Product Code: 3338
Availability: In Stock
$209.00
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Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.

Chemical Name 4-(4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one

Inhibitors Apoptosis Mdm2 Nutlin-3 890090-75-2
Biological Activity:
Biological Activity Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.
Technical Data:
M.W. 581.5
Formula: <p>C<sub>30</sub>H<sub>30</sub>Cl<sub>2</sub>N<sub>4</sub>O<sub>4</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 890090-75-2

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