Necrostatin-1

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Product Code: 3366
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Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.

Chemical Name 4-Imidazolidinone, 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo-

Biological Activity:
Biological Activity	Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.
Technical Data:
M.W.	259.33
Formula:	<p>C<sub>13</sub>H<sub>13</sub>N<sub>3</sub>OS</p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	4311-88-0
References:
References	Degterev A, et al. Nat Chem Biol, 2008, 4(5), 313-321. Degterev A, et al. Nat Chem Biol, 2005, 1(2), 112-119.

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Necrostatin-1

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