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RITA

RITA

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Product Code: 3280
Availability: In Stock
$335.00
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RITA (NSC 652287) induces both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks, and also inhibits MDM2-p53 interaction by targeting p53.

Chemical Name: 2-Thiophenemethanol, 5,5'-(2,5-furandiyl)bis-

Inhibitors Apoptosis p53 RITA 213261-59-7
Biological Activity:
Biological Activity RITA (NSC 652287) induces both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks, and also inhibits MDM2-p53 interaction by targeting p53.
Technical Data:
M.W. 292.37
Formula: <p>C<sub>14</sub>H<sub>12</sub>O<sub>3</sub>S<sub>2</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 213261-59-7
References:
References Rivera MI, et al. Biochem Pharmacol. 1999, 57(11), 1283-1295. Nieves-Neira W, et al. Mol Pharmacol. 1999, 56(3), 478-484. Issaeva N, et al. Nat Med. 2004, 10(12), 1321-1328. Ma T, et al. Biochem Biophys Res Commun. 2012, 417(3), 931-937. Saha MN, et al. PLoS One. 2012, 7(1), e30215. Krajewski M, et al. Nat Med. 2005, 11(11), 1135-1136, author reply 1136-1137.

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