VX-765

VX-765

Product Code: 3184
Availability: In Stock
$171.00
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VX-765 is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM.

Chemical Name:
(S)-1-((S)-2-(4-amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxo-tetrahydrofuran-3-yl)pyrrolidine-2-carboxamide

Biological Activity:
Biological Activity VX-765 is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Targets Caspase-1
Technical Data:
M.W. 509
Formula: C<sub>24</sub>H<sub>33</sub>ClN<sub>4</sub>O<sub>6</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 273404-37-8, 851091-96-8
References:
References Wannamaker W, et al. J Pharmacol Exp Ther. 2007, 321(2), 509-516. Ravizza T, et al. Neurobiol Dis. 2008, 31(3), 327-333. Maroso M, et al. Neurotherapeutics. 2011, 8(2), 304-315. [Akin D, et al. Neurobiol Dis. 2011, 44(3), 259-269.

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