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PAC-1

PAC-1

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Product Code: 3321
Availability: In Stock
$108.00
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PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.

Chemical Name (E)-N'-(3-allyl-2-hydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide

Inhibitors Apoptosis Caspase PAC-1 315183-21-2 315183-21-2
Biological Activity:
Biological Activity PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.
Technical Data:
M.W. 392.49
Formula: <p>C<sub>23</sub>H<sub>28</sub>N<sub>4</sub>O<sub>2</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 315183-21-2
References:
References Putt KS, et al. Nat Chem Biol, 2006, 2(10), 543-550. Peterson QP, et al. J Mol Biol, 2009, 388(1), 144-158. Seervi M, et al. Cell Death Dis, 2011, 2, e207.

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