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Ibrutinib

Ibrutinib

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Product Code: 3431
Availability: In Stock
$398.00
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Ibrutinib is a potent and highly selective Btk inhibitor with IC50 of 0.5 nM, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc.

Chemical Name (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

Inhibitors Angiogenesis BTK Ibrutinib 936563-96-1
Biological Activity:
Biological Activity Ibrutinib is a potent and highly selective Btk inhibitor with IC50 of 0.5 nM, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc.
Technical Data:
M.W. 440.5
Formula: <p>C<sub>25</sub>H<sub>24</sub>N<sub>6</sub>O<sub>2</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 936563-96-1
References:
References Honigberg LA, et al. Proc Natl Acad Sci U S A. 2010, 107(29), 13075-13080. Herman SE, et al. Blood. 2011, 117(23), 6287-6296. Chang BY, et al. Arthritis Res Ther. 2011, 13(4), R115. Ponader S, et al. Blood. 2012, 119(5), 1182-1189.

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