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Pazopanib HCl

Pazopanib HCl

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Product Code: 3316
Availability: In Stock
$180.00
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Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.

Chemical Name 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide hydrochloride

Inhibitors Angiogenesis VEGFR Pazopanib HCl 635702-64-6
Biological Activity:
Biological Activity Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.
Technical Data:
M.W. 473.98
Formula: <p>C<sub>21</sub>H<sub>23</sub>N<sub>7</sub>O<sub>2</sub>S.HCl</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 635702-64-6
References:
References Harris PA, et al. J Med Chem. 2008, 51(15), 4632-4640. Hosaka S, et al. J Orthop Res. 2012. Kernt M, et al. Retina. 2012.

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