GW441756

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Product Code: 3168
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GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2.

Chemical Name :

2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-

Biological Activity:
Biological Activity	GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2.
Technical Data:
M.W.	275.3
Formula:	C<sub>17</sub>H<sub>13</sub>N<sub>3</sub>O
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	504433-23-2
References:
References	Wood ER, et al. Bioorg Med Chem Lett, 2004, 14(4), 953-957. Eun Joo Jung, et al. Exp Mol Med, 2008, 40(3), 276–285. Jung EJ, et al. Mol Cells, 2008, 26(1), 12-17.

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