MGCD-265

MGCD-265

Product Code: 3381
Availability: In Stock
$398.00
-+

MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.

Chemical name: N-[[[3-Fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]amino]thioxomethyl]-benzeneacetamide

Biological Activity:
Biological Activity MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
Technical Data:
M.W. 517.60
Formula: <p>C<sub>26</sub>H<sub>20</sub>FN<sub>5</sub>O<sub>2</sub>S<sub>2</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 875337-44-3
References:
References Bonfils C. et al. AACR 2012 Annual Meeting, 2012. Abstract 1790. Beaulieu N. et al. 20th EORTC-NCI-AACR Symposium, 2008.

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