Tie2 kinase inhibitor

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Product Code: 3214
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Tie2 kinase inhibitor is an optimized compound of SB-203580, selective to Tie2 with IC50 of 0.25 μM, 200-fold more potent than p38.

Chemical Name:

4-(5-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)pyridine

Biological Activity:
Biological Activity	Tie2 kinase inhibitor is an optimized compound of SB-203580, selective to Tie2 with IC50 of 0.25 μM, 200-fold more potent than p38.
Technical Data:
M.W.	439.53
Formula:	C<sub>26</sub>H<sub>21</sub>N<sub>3</sub>O<sub>2</sub>S
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	948557-43-5
References:
References	Semones M, et al. Bioorg Med Chem Lett, 2007, 17(17), 4756-4760.

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