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PI-103

PI-103

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Product Code: 3311
Availability: In Stock
$335.00
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PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM.

Chemical Name Phenol, 3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]-

Inhibitors PI3K/Akt/mTOR DNA-PK PI-103 371935-74-9
Biological Activity:
Biological Activity PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM.
Technical Data:
M.W. 348.36
Formula: <p>C<sub>19</sub>H<sub>16</sub>N<sub>4</sub>O<sub>3</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 371935-74-9
References:
References Knight ZA, et al. Cell, 2006, 125(4), 733-747. Fan QW, et al. Cancer Cell, 2006, 9(5), 341-349. Raynaud FI, et al. Mol Cancer Ther. 2009, 8(7), 1725-1738.

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