SB216763

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Product Code: 3262
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SB216763 is a potent and selective GSK-3 inhibitor with IC50 of 34.3 nM for GSK-3α and equally effective at inhibiting human GSK-3β.

Chemical Name:
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Biological Activity:
Biological Activity	SB216763 is a potent and selective GSK-3 inhibitor with IC50 of 34.3 nM for GSK-3α and equally effective at inhibiting human GSK-3β.
Technical Data:
M.W.	371.22
Formula:	C<sub>19</sub>H<sub>12</sub>N<sub>2</sub>O<sub>2</sub>Cl<sub>2</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	280744-09-4
References:
References	Coghlan MP, et al. Chem Biol, 2000, 7(10), 793-803. Cross DA, et al. J Neurochem, 2001, 77(1), 94-102. Ougolkov AV, et al. Cancer Res, 2005, 65(6), 2076-2081. Gurrieri C, et al. J Pharmacol Exp Ther, 2010, 332(3), 785-794.

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