TWS119

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Product Code: 3197
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TWS119 is a GSK-3β inhibitor with IC50 of 30 nM; capable of inducing neuronal differentiation and may be useful to stem cell biology.

Chemical Name:
3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)phenol

Biological Activity:
Biological Activity	TWS119 is a GSK-3β inhibitor with IC50 of 30 nM; capable of inducing neuronal differentiation and may be useful to stem cell biology.
Technical Data:
M.W.	318.33
Formula:	C<sub>18</sub>H<sub>14</sub>N<sub>4</sub>O<sub>2</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	601514-19-6
References:
References	Ding S, et al, Pro Natl Acad Sci U S A, 2003, 100(13), 7632-7637. Ding S, et al, Nat Biotechnol, 2004, 22(7), 833-840. Kordes C, et al, Biochem Biophys Res Commun, 2008, 367(1), 116-123. Gattinoni L, et al, Nat Mediicine, 2009, 15(7), 808-813. Muralidharan S, et al, J Immunol, 2011, 187(10), 5521-5532.

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