T0901317

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Product Code: 3237
Availability: In Stock

$180.00

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T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively.

Chemical Name:
Benzenesulfonamide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-

Biological Activity:
Biological Activity	T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively.
Technical Data:
M.W.	481.33
Formula:	C<sub>17</sub>H<sub>12</sub>F<sub>9</sub>NO<sub>3</sub>S
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	293754-55-9
References:
References	Repa JJ, et al. Science, 2000, 289(5484), 1524-1529. Houck KA, et al. Mol Genet Metab, 2004, 83(1-2), 184-187. Mitro N, et al. FEBS Lett, 2007, 581(9), 1721-1726. Koldamova RP, et al. J Biol Chem, 2005, 280(6), 4079-4088. Kumar N, et al. Mol Pharmacol, 2010, 77(2), 228-236.

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