URB597

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Product Code: 3199
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URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets.

Chemical Name:
Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester

Biological Activity:
Biological Activity	URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets.
Technical Data:
M.W.	338.4
Formula:	C<sub>20</sub>H<sub>22</sub>N<sub>2</sub>O<sub>3</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	546141-08-6
References:
References	Mor M, et al. J Med Chem, 2004, 47(21), 4998-5008. [Piomelli D, et al. CNS Drug Rev, 2006, 12(1), 21-38. Tham CS, et al. FEBS Lett, 2007, 581(16), 2899-2904. Niforatos W, et al. Mol Pharmacol, 2007, 71(5), 1209-1216. Fegley D, et al. J Pharmacol Exp Ther, 2005, 313(1), 352-358. Jayamanne A, et al. Br J Pharmacol, 2006, 147(3), 281-288. [Bortolato M, et al. Biol Psychiatry, 2007, 62(10), 1103-1110. Realini N, et al. Neuropharmacology, 2011, 60(2-3), 235-243.

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