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Varespladib (LY315920)

Varespladib (LY315920)

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Product Code: 3194
Availability: In Stock
$335.00
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LY315920 (Varespladib) is a potent and selective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor with IC50 of 7 nM,. Phase 3.

Chemical Name:
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid

Inhibitors Metabolism Phospholipase (e.g. PLA) Varespladib (LY315920) 172732-68-2
Biological Activity:
Biological Activity LY315920 (Varespladib) is a potent and selective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor with IC50 of 7 nM,. Phase 3.
Technical Data:
M.W. 380.39
Formula: C<sub>21</sub>H<sub>20</sub>N<sub>2</sub>O<sub>5</sub>
Solubility: DMSO
Purity: 98%
Storage: C21H20N2O5
CAS No: 172732-68-2
References:
References Draheim SE, et al. J Med Chem. 1996, 39(26), 5159-5175. Snyder DW, et al. J Pharmacol Exp Ther. 1999, 288(3), 1117-1124. Hori Y, et al. Invest Ophthalmol Vis Sci. 2005, 46(11), 4050-4061.

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