Ozagrel

Ozagrel

Product Code: 3322
Availability: In Stock
$117.00
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Ozagrel is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM.

Chemical Name 3-​[4-​(1H-​imidazol-​1-​ylmethyl)phenyl]-​2E-​propenoic acid

Biological Activity:
Biological Activity Ozagrel is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM. It does not inhibit prostacyclin (PGI2) synthetase, cyclooxygenase or PGE2 isomerase (IC50 > 1 mM). Inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke and antihypertensive effects in spontaneously hypertensive rats.
Technical Data:
M.W. 228.25
Formula: <p>C<sub>13</sub>H<sub>12</sub>N<sub>2</sub>O<sub>2</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 82571-53-7

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