Apixaban

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Product Code: 3032
Availability: In Stock

$398.00

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Apixaban is a highly selective, reversible inhibitor of Factor Xa with K_i of 0.08 nM and 0.17 nM in human and rabbit, respectively.

Chemical name: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

Biological Activity:
Biological Activity	Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.
Technical Data:
M.W.	459.5
Formula:	C<sub>25</sub>H<sub>25</sub>N<sub>5</sub>O<sub>4</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	503612-47-3
References:
References	Pinto DJ, et al. J Med Chem. 2007, 50(22), 5339-5356. Wong PC, et al. J Thromb Haemost. 2008, 6(5), 820-829. Zhang D, et al. J Thromb Thrombolysis. 2010, 29(1), 70-80. He K, et al. Eur J Drug Metab Pharmacokinet. 2011, 36(3), 129-139.

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