QNZ

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Product Code: 3297
Availability: In Stock

$461.00

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QNZ (EVP4593) shows potent inhibitory activity toward bothNF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM, respectively.

Chemical Name 4,6-Quinazolinediamine, N4-[2-(4-phenoxyphenyl)ethyl]-

Biological Activity:
Biological Activity	QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM, respectively.
Technical Data:
M.W.	356.42
Formula:	<p>C<sub>22</sub>H<sub>20</sub>N<sub>4</sub>O</p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	545380-34-5
References:
References	Tobe M, et al. Bioorg Med Chem, 2003, 11(3), 383-391. VA Vigont, et al. Biochemistry (Mosc), 2012, 6(2), 206-214. Armstrong SJ, et al. Neurosci Lett, 2008, 439(1), 42-46. Li L, et al. J Cell Mol Med, 2009, 13(8B), 2684-2692. Yang RH, et al. Mol Pain, 2009, 28(5), 26.

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