PFI 3

PFI 3

Product Code: 6832
Availability: In Stock
$0.00
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Chemical Name: (2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one

Biological Activity:
Biological Activity Potent and selective polybromo 1 and SMARCA4 inhibitor (Kd values are 48 and 89 nM respectively). Also inhibits SMARCA2. Displays 30-fold selectivity over other sub-family branches. Accelerates FRAP recovery in cells at a concentration of 1 μM.
Technical Data:
M.W. 321.37
Formula: C19H19N3O2
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
References:
References

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