Bosentan Hydrate

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Product Code: 3075
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Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with K_i of 4.7 nM and 95 nM, respectively.

Chemical Name Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-, hydrate (1:1)

Biological Activity:
Biological Activity	Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
Technical Data:
M.W.	569.63
Formula:	<p>C<sub>27</sub>H<sub>29</sub>N<sub>5</sub>O<sub>6</sub>S.H<sub>2</sub>O</p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	157212-55-0
References:
References	Ostrowski RP, et al. Pathophysiology, 2003, 9(4), 249-256. Clozel M, et al. J Pharmacol Exp Ther, 1994, 270(1), 228-235.

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