GW3965 HCl

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Product Code: 3166
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GW3965 is a potent, selective LXRagonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively.

Chemical Name 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride

Biological Activity:
Biological Activity	GW3965 is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively.
Technical Data:
M.W.	618.51
Formula:	C<sub>33</sub>H<sub>31</sub>ClF<sub>3</sub>NO<sub>3</sub>.HCl
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	405911-17-3
References:
References	Collins JL, et al. J Med Chem. 2002, 45(10), 1963-1966. Joseph SB, et al. Proc Natl Acad Sci U S A. 2002, 99(11), 7604-7609. Leik CE, et al. Br J Pharmacol. 2007, 151(4), 450-456. Scholz H, et al. Diabetologia. 2009, 52(7), 1352-1362. Guo D, et al. Cancer Discov. 2011, 1(5), 442-456.

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