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Tariquidar

Tariquidar

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Product Code: 3229
Availability: In Stock
$209.00
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Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines. Phase 3.

Chemical Name:

3-Quinolinecarboxamide, N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-

Inhibitors Transmembrane Transporters P-gp Tariquidar 206873-63-4
Biological Activity:
Biological Activity Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines. Phase 3.
Technical Data:
M.W. 646.73
Formula: C<sub>38</sub>H<sub>38</sub>N<sub>4</sub>O<sub>6</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 206873-63-4
References:
References Martin C, et al. Br J Pharmacol, 1999, 128(2), 403-411. Robey RW, et al. Cancer Res, 2004, 64(4), 1242-1246. Mistry P, et al. Cancer Res, 2001, 61(2), 749-758. Walker J, et al. Eur J Cancer, 2004, 40(4), 594-605.

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