CP-91149

CP-91149

Product Code: 3099
Availability: In Stock
$133.00
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CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.

Chemical Name

5-chloro-N-((2S,3R)-4-(dimethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide

Biological Activity:
Biological Activity CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
Technical Data:
M.W. 399.87
Formula: C<sub>21</sub>H<sub>22</sub>ClN<sub>3</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 186392-40-5
References:
References Martin WH, et al. Proc Natl Acad Sci U S A, 1998, 95(4), 1776-1781. Aiston S, et al. J Biol Chem, 2001, 276(26), 23858-23866. Schnier JB, et al. Biochem Biophys Res Commun, 2003, 309(1), 126-134. Lerín C, et al. Biochem J, 2004, 378(Pt 3), 1073-107 Yoshida T, et al. J Pharmacol Sci, 2011, 115(3), 329-335.

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