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(-)-Huperzine A

(-)-Huperzine A

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Brand: HTC
Product Code: 3450
Availability: In Stock
$146.00
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(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Phase 4.

Chemical Name
(1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid

Inhibitors Neuronal Signaling GluR (-)-Huperzine A 102518-79-6
Biological Activity:
Biological Activity (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.
Technical Data:
M.W. 242.32
Formula: C<sub>15</sub>H<sub>18</sub>N<sub>2</sub>O
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 102518-79-6
Certificate of Analysis:
Certificate of Analysis
References:
References Zhao Q, et al. Eur J Pharmacol, 2002, 455(2-3), 101-107. Zhang HY, et al. Trends Pharmacol Sci, 2006, 27(12), 619-625. Wang R, et al. Acta Pharmacol Sin, 2006, 27(1), 1-26. Zheng CY, et al. J Neurosci Res, 2008, 86(11), 2432-2440.

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