Tosedostat (CHR2797)

Tosedostat (CHR2797)

Product Code: 3205
Availability: In Stock
$146.00
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CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2. Phase 2.

Chemical Name:
(S)-cyclopentyl 2-((R)-2-((S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl)-4-methylpentanamido)-2-phenylacetate

Biological Activity:
Biological Activity CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2. Phase 2.
Technical Data:
M.W. 406.47
Formula: C<sub>21</sub>H<sub>30</sub>N<sub>2</sub>O<sub>6</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 238750-77-1
References:
References Krige D, et al. Cancer Res, 2008, 68(16), 6669-6679.

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