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CHIR-99021 (CT99021) HCl

CHIR-99021 (CT99021) HCl

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Product Code: 3090
Availability: In Stock
$713.00
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CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; ability to distinguish between GSK-3 and its closest homologs Cdc2 and ERK2.

Chemical Name 6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile hydrochloride

Inhibitors Stem Cells & Wnt GSK-3 CHIR-99021 (CT99021) HCl 252917-06-9
Biological Activity:
Biological Activity CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; ability to distinguish between GSK-3 and its closest homologs Cdc2 and ERK2.
Technical Data:
M.W. 501.8
Formula: <p>C<sub>22</sub>H<sub>18</sub>Cl<sub>2</sub>N<sub>8.</sub>HCl</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 252917-06-9
References:
References Ring DB, et al. Diabetes, 2003, 52(3), 588-595. Bennett CN, et al. J Biol Chem, 2002, 277(34), 30998-31004. Mussmann R, et al. J Biol Chem, 2007, 282(16), 12030-12037.

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