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Fasudil

Fasudil

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Product Code: 3143
Availability: In Stock
$117.00
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Fasudil (HA-1077) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively.

Chemical Name 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline hydrochloride

Inhibitors Cell Cycle ROCK Fasudil 105628-07-7
Biological Activity:
Biological Activity Fasudil (HA-1077) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively.
Technical Data:
M.W. 327.83
Formula: C<sub>14</sub>H<sub>17</sub>N<sub>3</sub>O<sub>2</sub>S.HCl
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 105628-07-7
References:
References Ono-Saito N, et al. Pharmacol Ther, 1999, 82(2-3), 123-131. Asano T, et al. J Pharmacol Exp Ther, 1987, 241(3), 1033-1040. Asano T, et al. Br J Pharmacol, 1989, 98(4), 1091-1100. Negoro N, et al. Biochem Biophys Res Commun, 1999, 262(1), 211-215. Fukushima M, et al. Liver Int, 2005, 25(4), 829-838. Zhang J, et al. Clin Chim Acta, 2009, 401(1-2), 76-80. Sun X, et al. J Neuroimmunol, 2006, 180(1-2), 126-134.

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