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GW9662

GW9662

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Product Code: 3172
Availability: In Stock
$180.00
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GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγversus PPARα and PPARδ.

Chemical Name

Benzamide, 2-chloro-5-nitro-N-phenyl-

Inhibitors Metabolism PPAR GW9662 22978-25-2
Biological Activity:
Biological Activity GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ.
Technical Data:
M.W. 276.68
Formula: C<sub>13</sub>H<sub>9</sub>ClN<sub>2</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 22978-25-2
References:
References Leesnitzer LM, et al. Biochemistry, 2002, 41(21), 6640-6650. Seargent JM, et al. Br J Pharmacol, 2004, 143(8), 933-937. Bendixen AC, et al. Proc Natl Acad Sci U S A, 2001, 98(5), 2443-2448. Starkey K, et al. J Clin Endocrinol Metab, 2003, 88(1), 55-59. Collino M, et al. Kidney Int, 2005, 68(2), 529-536.

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