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Raltegravir (MK-0518)

Raltegravir (MK-0518)

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Product Code: 3291
Availability: In Stock
$259.00
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Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectively.

Chemical Name N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(2-(2-methyl-1,3,4-oxadiazole-5-carboxamido)propan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide

Inhibitors Microbiology Integrase Raltegravir (MK-0518) 518048-05-0
Biological Activity:
Biological Activity Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectively.
Technical Data:
M.W. 444.42
Formula: <p>C<sub>20</sub>H<sub>21</sub>FN<sub>6</sub>O<sub>5</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 518048-05-0
References:
References Hare S, et al. Proc Natl Acad Sci U S A. 2010, 107(46), 20057-20062. Hicks C, et al. Clin Infect Dis. 2009, 48(7), 931-939. Moss DM, et al. Antimicrob Agents Chemother. 2012, 56(6), 3020-3026. [Hare S, et al. Mol Pharmacol. 2011, 80(4), 565-572. Lewis MG, et al. Retrovirology. 2010, 7, 21.

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