Rosuvastatin Calcium

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Product Code: 3274
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Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM.

Chemical Name:
2-[(1-Methylpropyl)dithio]-1H-imidazole

Biological Activity:
Biological Activity	Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM.
Technical Data:
M.W.	500.57
Formula:	C<sub>22</sub>H<sub>28</sub>FN<sub>3</sub>O<sub>6</sub>S.1/2Ca
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	147098-20-2
References:
References	Schneck DW, et al. Clin Pharmacol Ther, 2004, 75(5), 4554-63. Watanabe M, et al. Bioorg Med Chem, 1997, 5(2), 437-444. Kim YS, et al. J Cardiovasc Pharmacol, 2007, 49(6), 376-383. Carswell CI, et al. Drugs, 2002, 62(14), 2075-2085 [Stalker TJ, et al. Br J Pharmacol, 2001, 133(3), 406-412. Sch?fer A, et al. Biochem Pharmacol, 2007, 73(9), 1367-1375. Bulhak AA, et al. Acta Physiol Scand, 2005, 183(2), 151-159. Custodis F, et al. Cardiovasc Res, 2006 Jul 15, 71(2), 342-351. Dansette PM, et al. Exp Toxicol Pathol, 2000, 52(2), 145-148.

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