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Gefitinib

Gefitinib

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Brand: Cayman Chemical
Product Code: 3154
Availability: In Stock
$180.00
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Gefitinib (ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.

Chemical Name : N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Inhibitors Protein Tyrosine Kinase EGFR Gefitinib 184475-35-2
Biological Activity:
Biological Activity Gefitinib (ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.
Technical Data:
M.W. 446.90
Formula: C<sub>22</sub>H<sub>24</sub>ClFN<sub>4</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 184475-35-2
References:
References Pedersen MW, et al. Br J Cancer. 2005, 93(8), 915-923. Moasser MM, et al. Cancer Res. 2001, 61(19), 7184-7188. Williams KJ, et al. Br J Cancer, 2002, 86, 1157–1161. Ciardiello F, et al. Clin Cancer Res. 2000, 6(5), 2053-2063. Sirotnak FM, et al. Clin Cancer Res. 2000, 6(12), 4885-4892.

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